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HARNACK LECTURE · LIVE EVENT 17 February 2021 · 7:00 p.m. · CET |
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LECTURE |
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Innovation by Evolution: Bringing New Chemistry to Life Evolution – the adaption of species to different environments – has created an enormous diversity of life. In the early 1990s, Frances Arnold used the same principles – genetic change and selection – to pioneer methods of „directed evolution“ to create new proteins not found in nature. The process involved inducing random mutations and screening the resulting enzymes for sought-after properties. Arnold’s discovery was hugely important – creating a completely new way to design and produce pharmaceuticals and renewable fuels for a greener transport sector. In her talk, Frances Arnold will describe how lessons from nature inspired the development of methods for directed evolution. How is it possible to build sustainable, biological routes to important fuels and chemicals? Evolution, the most powerful biological design process, can also innovate, generating new enzyme catalysts, with a little insight from chemistry. Whole families of new-to-nature enzymes increase the scope of molecules and materials we can build using synthetic biology and move us closer to a sustainable world where human-invented chemistry will be genetically encoded. |
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SPEAKER |
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